This article was translated from the original Portuguese. Português

Carmen Reis asks:
Free PSA/total PSA ratio of 0.28. Is there any risk?
The free/total PSA ratio is a parameter widely used by urologists to identify men with a higher likelihood of being diagnosed with prostate cancer.
Studies in the medical literature validated its results in men with PSA > 4 ng/ml, but urologists tend to use it from PSA levels > 2.5 ng/ml.
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Book via WhatsApp Prostate cancer guideWhen the free/total PSA ratio is below 20%, there is an approximately 25% chance of finding prostate cancer on biopsy.
To answer your question... a ratio above 28% is not, on its own, a parameter that leads to recommending a prostate biopsy.
The digital rectal exam, the rate of increase in total PSA and, more recently, prostate MRI are other parameters also widely used by urologists in the screening stage of the disease.
When at least one of these parameters is abnormal, a prostate biopsy is needed to reach a definitive diagnosis.
To learn more about PSA, watch this video: here
Dr. Bruno Benigno
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Book via WhatsApp Prostate cancer guideThis content is educational and does not replace a medical consultation. Each case must be assessed individually, based on AUA, EAU and NCCN guidelines.




